Global Stem Cells Group to Participate in the IIIº World Congress on Clinical and Esthetic Research in Cordoba, Argentina May 16 and 17, 2015
GlobalStemCellsGroup.com has announced plans to participate in the IIIº World Congress on Clinical and Esthetic Research May 16 and 17, 2015. More than 500 physicians from Argentina, Mexico, Peru, Ecuador, Uruguay, El Salvador, Venezuela, Spain, Chile, Cuba and the U.S. are expected to attend, including specialists in aesthetic medicine, dermatology, plastic surgery, cosmetology, physiotherapy, nutrition and dentistry.
Following the conference, Global Stem Cells Group will conduct an intensive, hands-on course on stem cell harvesting, isolation and re-integration for qualified practitioners.
Hosted by the Association of Clinical and Esthetic Research (ACER), the event’s organizing committee has designed a program highlighting nationally and internationally renowned physicians and esthetic practitioners as featured speakers. The goal is to exchange clinical and scientific findings, and to grow academically.
The event will be held at the Hotel Amerian in the City of Villa Carlos Paz, Córdoba.
For more information visit the IIIº World Congress on Clinical and Esthetic Research website.
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Global Stem Cells Group to Host Featured Speaker at The Aesthetic Meeting 2015 in Montreal
Global Stem Cells Group Advisory Board member Alfredo Hoyos, M.D., will be a featured speaker at The Aesthetic Meeting May 14-19, 2015. Hoyos will promote the company’s new stem cell assisted fat transfer training course for medical professionals.
Global Stem Cells Group today announced plans to attend The Aesthetic Meeting 2015, an annual gathering of aesthetic medicine experts and innovators. GSCG Advisory Board member Alfredo Hoyos, M.D., is scheduled to introduce the company’s brand new training course that combines facial fat transfer injection techniques with adipose-derived stem cell techniques.
The course is designed to address the primary issues that concern patients in the aesthetic field, including facial aging caused by volume loss.
The Aesthetic Meeting is one of the aesthetic surgery industry’s biggest annual events, attracting leading educators, researchers and practitioners from around the world to discuss evidence-based medicine in aesthetic plastic surgery. According to organizers, it is an opportunity to meet with physicians who specialize in aesthetic plastic surgery of the face and body, and learn what advances are being made in the aesthetics field. This year’s meeting will also focus on what to expect beyond 2015 in the world of aesthetic and anti-aging medicine.
Dedicated exclusively to aesthetic surgery and cosmetic medicine education, The Aesthetic Meeting will offer attendees an array of new techniques, key research findings, and helpful information that physicians can apply in their own practice. The Aesthetic Meeting 2015 features a number of special presentations, panels and papers by surgeons with vast experience in aesthetic surgery. Additionally, you’ll gain valuable insights and pearls of wisdom from our international colleagues, as they often have the opportunity to implement new therapies, devices and techniques before they reach the U.S.
The Aesthetic Meeting 2015 will be held at the Palais des Congrès de Montréal in Montréal, from May 14 – 19, 2015. For more information, visit the The Aesthetic Meeting website, visit the Global Stem Cells Group website, email bnovas(at)stemcellsgroup(dot)com, or call 305.224.1858.
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The different types of stem cells and their current uses
Stem cells offer great potential for use in clinical applications thanks to their ability to specialize into different cell types and to renew themselves. Although some of them have limitations, stem cells are still an amazing resource for the medical world, as no other cell inside the human body has the ability to generate new cell types with a more specific function that the source.
Stem cells can be considered the body’s raw building blocks, as all the other cells with specialized functions result from stem cells that divide and give birth to daughter cells. These cells, at their turn, divide or differentiate and become specialized, giving birth to muscle, bone, blood, brain or other specific cell types.
The characteristics and applications of stem cells vary not only depending on the type of cells they differentiate into, but also on the nature of the tissue they are derived from. From this point of view, stem cells can be classified into three main groups: embryonic, adult and induced pluripotent stem cells.
Types of stem cells depending on origin
Embryonic stem cells (ESCs) come from embryos of up to 5 days old, and are pluripotent, meaning that they can divide into several stem cells and specialize into any type of cell. This property allows embryonic stem cells to repair damaged tissues and organs and to stimulate the regeneration of diseased tissues. Researchers can grow and induce the differentiation of ESCs in the lab, but the use of embryonic stem cells is often avoided due to ethical considerations.
Adult stem cells, the second type, are found in adult tissues inside the human body and they can also differentiate into various cell types, but their ability to give birth to new cells is limited. Although until recently it’s been thought that an adult stem cells can only differentiate into the same type of cell as the tissue it comes from, emerging studies suggest that these cells, just like ESCs, can create unrelated cell types.
In other words, just like an embryonic stem cell derived from bone marrow can give birth to liver or muscle cells, adult stem cells taken from bone marrow can create bone or skin cells. There’s a limit though, as adult stem cells can’t be manipulated as efficiently as ESCs, and they’re not as versatile and the ones derived from embryos.
The third type of stem cells is somewhere in between the adult and embryonic stem cells, and it’s called induced pluripotent stem cells (iPSCs). These are highly versatile, similarly to ESCs, but are made from adult specialized cells through laboratory techniques (genetic reprogramming). iPSCs have two main advantages: first one’s that they do not create any ethical debate, as they don’t come from embryos, and the second one is that the risk of rejection is lower than in adult stem cells, thanks to the fact that iPSCs are reprogrammed to act as ESCs.
Current applications of stem cells by type
We won’t discuss the ESCs here as the tendency is to not use embryonic stem cells, and opt for adult or induced pluripotent stem cells instead.
Perhaps the most used of all adult stem cells are those obtained from the bone marrow (mesenchymal stem cells), which can be differentiated into bone, cartilage and fat cells, and can encourage the production of new blood cells. These were not proven to be able to differentiate in any type of cell inside the human body, but existing research suggests mesenchymal stem cells may be useful in bone and cartilage repair or blood vessel repair after a heart attack [5].
In lab studies, bone marrow stem cells from adult rats were able to partially regrow the damaged liver, and to have beneficial effects when injected into the damaged heart. Also, scientists at the Children’s Hospital Boston have found adult bone marrow stem cells to protect against chronic lung disease [2] in mice models.
Induced pluripotent stem cells have also been tested for their ability to differentiate, and lab results showed that iPSCs made from skin samples may be useful in treating neurological disorders like Parkinson’s disease or Down’s syndrome [8].
Researchers in Japan managed to generate human liver buds from induced pluripotent stem cells, the scientists using three different types of stem cells for this purpose: part of them were hepatocytes coaxed from iPSCs, others were endothelial stem cells and others were mesenchymal stem cells. The liver buds were grown in vitro for a few days then transplanted to mice, where they quickly connected with the blood vessels and continued to grow.
Other studies have shown that iPSCs grown from embryonic cord-blood cells can be used for repairing the damaged retina of mice and regrowing the vascular vessels. Scientists from the Japan Ministry Health are currently conducting a clinical trial using autologous iPSCs in six patients affected by age-related macular degeneration. IPSCs used for this trial are derived from skin cells, and reprogrammed to differentiate into retinal pigment epithelial cells.
Adult stem cells have been used in treating leukemia and blood or bone related cancers utilizing bone marrow transplants [1]; mesenchymal stem cells have been shown to help in repairing the damaged cartilage in patients with articular cartilage defects [3] and to improve the outcome in spinal cord injuries [4]. Peripheral vascular disease [6] and liver cirrhosis [7] may also be treatable with adult stem cells.
Although adult stem cells and iPSCs can be differentiated in a wider variety of cells, not all of them have been tested in human subjects, one of the biggest barriers being the potential immunological rejection.
References
[1] http://en.wikipedia.org/wiki/Adult_stem_cell
[2] http://www.childrenshospital.org/news-and-events/2009/december-2009/bone-marrow-stem-cells-may-prevent-chronic-lung-disease
[3] http://www.ncbi.nlm.nih.gov/pubmed/18038395
[4] http://www.pubstemcell.com/monthly/006030700113.htm
[5] http://stemcells.nih.gov/info/scireport/pages/chapter9.aspx
[6] http://www.ncbi.nlm.nih.gov/pubmed/21671823
[7] http://www.ncbi.nlm.nih.gov/pubmed/16778155
[8] http://www.eurostemcell.org/factsheet/stem-cell-research-therapy-types-stem-cells-and-their-current-uses#iPS
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Global Stem Cells Group To Join GTCbio Stem Cell and Regenerative Medicine Summit in Boston, April 27-29, 2015
Global Stem Cells Group will attend the world-class GTCbio conference at the Hyatt Regency Boston Hotel, April 27-29. The event will showcase the latest developments in all areas of regenerative medicine, stem cell research and business.
Global Stem Cells Group has announced plans to attend the GTCbio Stem Cell Summit 2015 April 27 – 29, 2015 in Boston. This world-class summit will present the latest developments in all areas of stem cell research including applications, biology, medicine, regulations, and the business of stem cells and regenerative medicine.
The conference will address recent developments in pre-clinical and clinical trials, as well as translational research in stem cell therapies, regenerative medicine, tissue engineering, stem cell reprogramming and regulatory guidance. There will be an additional focus on business opportunities in stem cell medicine and its challenges, and discussions on potential strategies for overcoming these challenges.
The GTCbio Summit includes two parallel conferences with joint sessions on stem cell research in the diabetes space, and stem cell therapies from bench to bedside. Both conferences will also feature a lineup of 34 distinguished speakers from a broad spectrum in the medical community. Keynote speakers for both conferences include Masayo Takahashi, MD, PhD, CDB Ophthalmologist, Center for Developmental Biology; Douglas Melton, PhD, Professor & Investigator, Harvard Medical School, and Rudolf Jaenisch, MD, Professor of Biology, Massachusetts Institute of Technology.
Conference A: The 12th Stem Cell Research & Regenerative Medicine Conference discussion topics include:
Cells for Therapeutic Development & Drug Discovery
Advances in Adult & Pluripotent Stem Cells
Tissue Engineering
Immunotherapy: Revolution in Cancer Treatments
Joint Session: Regulatory Challenges in Cell Therapy
Conference B: The 4th Stem Cell Product Development & Commercialization Conference discussion topics include:
Manufacturing & Product Development
Challenges in Developing Clinical Efficacy
Funding Opportunities
Commercialization: Creating Sustainable Business Models
Joint Session: Regulatory Challenges in Cell Therapy
The GTCbio Summit 2015 will be held at the Hyatt Regency Boston Hotel. For more information, visit the summit website. To learn more about Global Stem Cells Group, visit the GSCG website, email bnovas(at)stemcellsgroup(dot)com, or call 305-560-5337.
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Global Stem Cells Group Signs Consortia Innovas, SA to Exclusive Representative Contract for Chile Territory
Global Stem Cells Group has announced an exclusive representative contract with Chilean health management, development and biotechnology company Consortia Innovas, SA.
Global Stem Cells Group, Inc. has signed an exclusive representative contract with Consortia Innovas, SA, a Santiago, Chile-based health management, development and biotech company. Founded by entrepreneur Enrique Testart, M.D., Consortia Innovas focuses on helping patients gain access to the latest medical treatments regenerative medicine has to offer.
According to Global Stem Cells Group Founder Benito Novas, Testart searches the globe for innovative stem cell companies that fit in with the Chilean markets, and Global Stem Cells Group turned out to be a perfect fit. Innovas will be in charge of all Global Stem Cells Group divisions and programs in Chile, including patient recruiting through Cellgenic, physician training and certification trough Stem Cell Training, and stem cell equipment and disposables sales through Adimarket.
Cellgenic, Stem Cell Training and Adimarket are all subsidiaries of the Global Stem Cells Group brand.
“Our main objective is to organize Chile’s first symposium on Stem Cells and Regenerative Medicine in Santiago in early 2015,” Novas says. “Our new alliance with Consortia Innovas will allow us to establish our brand as the leader in regenerative medicine therapies in Chile.”
The first annual Global Stem Cells Symposium is scheduled to take place in Buenos Aires Oct 2, 2014, to be preceded by an intensive two-day hands-on training course in stem cell harvesting, isolation and applications Sept. 27 and 28 at Santiago’s Innovas facilities.
The key to Global Stem Cells Group’s strategy to expand into foreign markets by recruiting local representatives and distributors like Consortia Innovas to help manage the company’s growth in a specific geographic area. Global Stem Cells group requires any company under consideration for the expansion program to have more than five years experience in the health care industry with at least some experience in the field of regenerative medicine .
In addition, geographic alliances require a commitment to a number of stem cell training courses during a one-year period, certification of physicians, and willingness to organize a large medical meeting or symposium in their territory.
About Consortia Innovas SA:
Consortia Innovas SA is comprised of a cluster of organizations designed to address the different needs of a new generation of consumers. With more than 20 years’ experience in the public and private sectors, Consortia Innovas specializes in designing customized B2B and B2C models for each central or regional organization, providing innovative services and diagnostic precision determined by local needs.
Consortia Innovas offers innovative and flexible technological and communication resources that enhance the skills of people in the management, operation and marketing fields. For more information, visit the Consortia Innovas SA website, Email contacto@innovas.cl, or call +56 2 2692 3650.
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Global Stem Cells Group to Hold Practical Adipose-Derived Stem Cell Harvesting, Isolation and Re-integration Training Course in Santa Cruz, Bolivia
In conjunction with Regenerative Medicine Arroyo, Global Stem Cells Group has announced plans to hold a hands-on, intensive stem cell training course in Santa Cruz, Bolivia, April 4 and 5, 2015.
Global Stem Cells Group and its subsidiary, Stem Cells Training, has coordinated with Emil Arroyo, M.D. and Horacio Oliver, M.D. to conduct the first of four stem cell training courses planned for Bolivia in 2015. Devised to meet the increasing demand for regenerative medicine techniques in the region, the first adipose derived harvesting, isolation and re-integration training course will take place April 4 and 5, 2015, in Santa Cruz.
The two-day, hands-on intensive training course was developed for physicians and high-level practitioners to learn the techniques in harvesting and reintegrating stem cells derived from adipose tissue and bone marrow. The objective of the training is to provide physicians with practical stem cell medicine techniques they can use in-office to treat a variety of conditions in their patients.
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Global Stem Cells Group to Participate in the 25th Argentine Congress of Aesthetic Medicine in Buenos Aires April 9-10, 2015
Global Stem Cells Group will conduct a specialized course for qualified medical professionals on stem cell harvesting, isolation and re-integration on April 11, following the Congress on aesthetic medicine.
GlobalStemCellsGroup.com has announced plans to participate in the 25th annual Argentine Congress of Aesthetic Medicine April 9 and 10 2015. More than 1,000 physicians from around the world will descend on Buenos Aires for the conference to learn and share new findings in aesthetic medicine.
Following the congress, Global Stem Cells Group and Estanislao Janowski, M.D., a plastic surgeon specializing in stem cell application in aesthetic and cosmetic medicine will conduct an intensive, hands-on course on stem cell harvesting, isolation and re-integration, to be held April 11. Janowski, a GSCG faculty member and long-time collaborator is the owner and president of Bioplastica, an aesthetic surgical center featuring the latest stem cell applications in cosmetic and anti-aging medicine.
This will be the third year Global Stem Cells Group participates in the conference, hosted by the Argentina Society of Aesthetic Medicine (SOARME). A soon-to-be-named GSCG faculty member will also deliver a keynote speech to congress attendees.
The international event, which will be held at the Catholic University of Argentina in Buenos Aires, will feature acclaimed stem cell aesthetic practitioners from Argentina and the U.S. SOAME is a member of the Argentine Medical Association (A.M.A.) and of the International Union of Aesthetic Medicine (U.I.M.E.). SOAME has the scientific support of the John F. Kennedy University in Buenos Aires and a host of national and international scientific organizations.
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Global Stem Cells Group Announces Alliance with HANK Bioengineering Co., Ltd. in Shenzhen, China
The Global Stem Cells Group has established a collaborative alliance with HANK Bioengineering Co., Ltd. of Shenzhen, China.
Global Stem Cells Group.com has announced a newly formed alliance with Shenzhen HANK Bioengineering Co., Ltd. and its Chinese-American founder Mingjie Zhang, M.D., Ph.D. The alliance will establish a stem cells training course in the City of Shenzen, Guangdong Province, China in September 2015.
Shenzhen HANK is a biotechnology company established in 2013 by Zhang, an award-winning scientist, microbiologist and virologist, to integrate research, development, production, and sales of biomedical products. Zhang worked at the U.S. Centers for Disease Control from 1991 to 1993, the U.S. National Institute of Health (NIH) from 1993 to 1994, and the U.S. Food and Drug Administration from 1995 to 2013 in various research positions including National Research Center (NRC) senior associate from 1995 to 1997. In 2012 he earned the Scientific Achievement Award from the USFDA for outstanding achievement in natural killer (NK) cell research, and holds numerous awards for his work in the fields of HIV, HCV, West Nile virus, Japanese encephalitis virus, and quality performance.
In 2013, Dr. Zhang expanded on his work in stem cell research and development by launching HANK Bioengineering Co. Ltd. in Shenzhen, China. HANK is a 4,300 square foot (400 square meters) CFDA certified cGMP facility affiliated with HANK Bioengineering Institute’s Cell Biology and Molecular Immunology Laboratories. HANK has established close collaborations with more than five hospitals in China for clinical applications of its cell therapy products.
Shenzhen HANK is also a biotechnology service provider committed to the development and application of multiple immune cell therapy systems. The company has up to 20 cell therapy products of 4 series approved by the CFDA, including lymphocyte culture medium (NK, CTL and Treg cell in vitro culture reagents), lymphocyte serum-free culture medium, lymphocyte separation media, and lymphocyte freezing medium.
“Dr. Zhang and HANK Bioengineering will work seamlessly with our research, product development and education programs,” says Benito Novas, Global Stem Cells Group CEO. “This is a great opportunity for us to expand into China and work with one of the world’s most accomplished cell therapy researchers in his certified, cutting-edge cell biology laboratories.”
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Mario Camacho Alcocer Joins Global Stem Cells Group Faculty
The Global Stem Cells Group has announced the addition of Biomedical Researcher Mario Camacho Alcocer to its faculty.
GlobalStemCellsGroup.com has recruited Mario Camacho Alcocer to the company’s growing faculty. Camacho Alcocer, a biomedical researcher and founding partner of Criogenix SA de CV in Queretaro, Mexico, will join GSCG’s team of biomedical professors who will teach the “Diplomat in Cell Therapy and Tissue Engineering” program.
Criogenix SA de CV is a private company registered in the National Record of Scientific and Technological Institutions and Companies in Mexico (RENIECYT).
Camacho Alcocer will teach two-day, interactive training courses on adult stem cell extraction and re-integration to physicians and qualified medical practitioners who wish to learn and use the process in their practices.
Camacho Alcocer is accomplished in generating and applying new stem cell therapeutic protocols and technologies. His current research focuses on extracellular matrix interactions to regulate the dynamic of defined stem cells populations, with a goal to regenerate functional capabilities of specific tissues (or to develop tissues in vitro), as well as the development of specific scaffolds for cell culture. His research is central to Criogenix SA de CV’s development of a major integral stem cell unit management system for therapeutic applications.
Global Stem Cells Group and StemCell Center are expanding the company’s clinical presence worldwide by partnering with experienced and qualified regenerative medicine physicians to open new clinics licensed and developed under the Cellgenic banner.
In 2014, Global Stem Cells Group expanded its StemCell Center’s global presence to 20 countries. Cellgenic offers stem cell treatments to help treat a variety of diseases and conditions including arthritis, autism, chronic obstructive pulmonary disease (COPD), diabetes, and pain due to injuries at various facilities worldwide.
Cellgenic is certified for the medical tourism market, and staff physicians are board-certified or board-eligible. Cellgenic clinics provide services in more than 10 specialties, attracting patients from the United States and around the world.
The Global Stem Cells Group is committed to the highest standards in service and technology, expert and compassionate care, and a philosophy of exceeding the expectations of their international patients.
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Global Stem Cells Group, Inc. Announces Launch of New Stem Cell Harvesting Products
Global Stem Cells Group and Cellgenic announce the launch of two new kits for physicians to use in isolating and harvesting stem cells from bone marrow and adipose tissue based on Adistem technology.
In answer to industry-wide requests for more accessible solutions to stem cell procedures, Global Stem Cells Group, Inc. and Cellgenic have announced the launch of two new stem cell harvesting and isolation kits.
The Cellgenic BMAC 60 mL concentrating system is a high performing concentrating system for bone marrow aspirate. This kit come complete with a bone marrow filter, a bone marrow aspirating needle and a locking syringe to help maintain suction during the aspirating process. The BMAC 60 kit includes bone marrow concentrate up to 11 times the baseline values, to produce 6-8 mL BMC from a 60 mL sample of bone marrow aspirate.
The Cellgenic 60 mL Adipose Derived Stem Cell (ADSC) Kit System includes all the tools and consumables for the extraction of adipose-derived stem cells from 60 mL of lipoaspirated fat. The ADSC kit is currently being used in clinical procedures for lung disease, intra-articular injections for osteoarthritis of the knee and hip, cosmetic surgery and acne scarring, dermal injections, stem cell enriched fat transfer, wounds, chronic ulcers and other chronic conditions. The enzymatic component used to obtain the stromal vascular fraction (SVF) is provided by Adistem.
The Cellgenic ADSC Kit System is available in three versions:
Gold, to conduct in-office stem cell procedures with certified GMP components for reliable performance.
Platinum, with all the benefits of the basic (gold) kit plus a sterilized PRP close system with vortex engineering method to minimize platelet loss. One set of individually packed Tulip Gems instruments are added for safe and precise adipose tissue extraction.
Titanium, the perfect state-of-the-art deluxe kit system used by a growing number of regenerative medicine physicians and recognized as the perfect preparation for virtually all clinical applications. Built with Emcyte technology, the Cellgenic Titanium kit has been independently reviewed and proven in various critical performance points that make a difference in patient outcomes.
The Titanium kit is currently being used in topical procedures such as intra-articular injection for osteoarthritis of the knee and hip, cosmetic surgery and acne scarring, dermal injection, stem cell enriched fat transfer, wounds chronic ulcers among other chronic conditions.
According to Global Stem Cells Group CEO Benito Novas, the entire Global Stem Cells Group faculty and scientific advisory board worked together to develop the kits.
“These new products will help us carry out our mission to provide accessible GMP certified kits to our member client, ensuring that more patients will be able to gain access to these therapies,” says Novas. “We are confident that the regenerative medicine industry will be excited to receive these products.”
About Adistem:
AdiStem Ltd. is a provider of photo-activation technology and medical solutions that assist in orthopedic, cosmetic, neurologic, pulmonary, metabolic and plastic/reconstructive surgery procedures.
The company owns proprietary technology for PRP procedures and for autologous adult adipose-derived stem cell isolation and administration. The use of AdiLight-2 for the photo activation of PRP requires no training. On the other hand, the adult stem cell technology is shared with qualified clinicians through instructional courses, workshops and seminars.
AdiStem has also isolated specific biomolecules from autologous adult adipose-derived stem cells that target a number of chronic diseases including HIV/Aids, pain, and Type II diabetes.
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